Cheesy Meatloaf Casserole

Update : February 20, 2026

why make this recipe

Cheesy Meatloaf Casserole is a comforting and delicious dish that brings together two favorites: meatloaf and cheesy goodness. It’s perfect for family dinners and easy to prepare. Plus, it’s a one-dish meal, which means less cleanup for you. This recipe is also budget-friendly, making it a great choice for weeknight meals.

how to make Cheesy Meatloaf Casserole

Ingredients :

1 lb ground beef
1 cup breadcrumbs
1 egg
1/2 cup onion, chopped
1 cup shredded cheese (cheddar or mozzarella)
1/2 cup milk
1 tsp garlic powder
1 tsp salt
1/2 tsp pepper
1 cup ketchup (for topping)

Directions :

Preheat the oven to 350°F (175°C).
In a large bowl, combine ground beef, breadcrumbs, egg, chopped onion, shredded cheese, milk, garlic powder, salt, and pepper. Mix well.
Transfer the mixture to a greased baking dish and spread it evenly.
Spread ketchup over the top of the mixture.
Bake for 45-50 minutes, or until the meat is cooked through.
Let it cool for a few minutes before serving.

how to serve Cheesy Meatloaf Casserole

Serve Cheesy Meatloaf Casserole warm, cut into squares. It pairs well with mashed potatoes, green beans, or a fresh salad. You can also sprinkle some extra cheese on top for added flavor.

how to store Cheesy Meatloaf Casserole

To store leftovers, let the casserole cool completely. Then, cover it with plastic wrap or transfer it to an airtight container. It will last in the refrigerator for up to three days. You can also freeze it for up to three months. To reheat, simply warm it in the oven or microwave until heated through.

tips to make Cheesy Meatloaf Casserole

For extra flavor, try adding herbs like parsley or Italian seasoning to the meat mixture.
Use different types of cheese if you prefer, such as mozzarella or a mix of cheeses.
If you like a bit of spice, consider adding some chopped jalapeños or crushed red pepper flakes.

variation

You can make a turkey version of this casserole by swapping out ground beef for ground turkey. This makes it a leaner option while still being delicious. You can also add vegetables, such as bell peppers or carrots, to boost the nutrition.

FAQs

Can I use frozen ground beef for this recipe?
Yes, but be sure to thaw it completely before mixing it with the other ingredients.

What can I substitute for breadcrumbs?
You can use crushed crackers, oats, or even cooked rice as a substitute for breadcrumbs.

Is it necessary to add ketchup on top?
No, you can skip the ketchup if you prefer or use barbecue sauce or a cheese sauce instead for a different flavor.